Beilstein J. Org. Chem.2020,16, 1881–1900, doi:10.3762/bjoc.16.156
, India Department of Physics, S.V.D. College, Kadapa-516003, Andhra Pradesh, India 10.3762/bjoc.16.156 Abstract Naturaldolomiticlimestone (NDL) is employed as a heterogeneous green catalyst for the synthesis of medicinally valuable benzimidazoles, dihydropyrimidinones, and highly functionalized
: benzimidazoles; dihydropyrimidinones; highly substituted pyridines; naturaldolomiticlimestone; ultrasound irradiation; Introduction
Nitrogen heterocycles are recognized as “privileged medicinal scaffolds” because these compounds are found in a wide variety of bioactive natural products and pharmaceuticals [1
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Graphical Abstract
Figure 1:
The benzimidazoles I–IV, dihydropyrimidinones/-thiones V–VIII, and 2-amino-4-aryl-3,5-dicarbonitril...